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Splice

Horror · Science Fiction

Splice

She's not human...not entirely.

5.9(2,475) 6/3/2010 1h 44m
HorrorScience Fiction

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

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Trailer

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Top Cast

Adrien Brody

Adrien Brody

Clive

Sarah Polley

Sarah Polley

Elsa

Delphine Chanéac

Delphine Chanéac

Dren

David Hewlett

David Hewlett

Barlow

Abigail Chu

Abigail Chu

Young Dren

Stephanie Baird

Stephanie Baird

Elsa / PD

Brandon McGibbon

Brandon McGibbon

Gavin

Amanda Brugel

Amanda Brugel

Melinda Finch

Directed by

Vincenzo Natali

Production

Reviews

Andres Gomez

5/10

11/26/2014

The FX is OK and the uneasiness and thrill is always there but the script is stereotypical, weak and full of holes.

John Chard

6/10

12/2/2018

Brundledren! Splice is a tricky picture to evaluate, for its ideas are superb. One could argue that it brings a new petri dish full of meddling scientists facing the consequences of their actions, while conversely it justifiably feels like a Cronenberg knock-off. Psychological discord is in abundance, with its slants on skew-whiff parenting giving the pic a dark fascination, and as unpleasant as the male fantasy angle is, it does hold a morbid interest factor. Yet come the final third the makers let things run away from them, the bonkers dangers of tampering with science giving way to daft schlock, even managing to be distasteful in the process - while the finale is a weak attempt at a "TBC" cliff hanger. Lead cast members are turning in good perfs. Adrien Brody and Sarah Polle

CinemaSerf

5/10

10/26/2022

"Clive" (Adrien Brody) and "Elsa" (Sarah Polley) are a couple of genetic engineers charged by David Hewlett's "Barlow" with discovering an important gene that could lead to huge advances in medical science. Using a mix of human and animal DNA that have varying degrees of success before the evolution of a creature "Dren" (Delphine Chanéac) that develops more human attributes - as well as a tail with a stinger and the ability to grow wings. As we progress through this frankly rather disturbing story, we discover that "Elsa" quite literally has skin in the game as they must both seek to protect their creation from not just their employers but from her increasingly violent and lustful tendencies. I was quite interested in the underlying premise but the execution here is really poor. I never di

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